Tag Archives: cognitive disorders

Searching for Autism in our Social Brain

All animals need to know and communicate with their own, so evolution has developed in every brain the ways we all recognize and socialize with each other.

But while other brains are social – no other brain is as social, or can do what the human brain can – and as far as science knows – it also seems that no other brain can suffer from conditions like autism. Are these two fortunes somehow linked?

That is a question that many are asking, including Alysson Muotri’s lab at the Sanford Consortium for Regenerative Medicine. They are using brain organoids to unravel this mystery, but where do they start looking for the root causes of these conditions?

Enter Katerina Semendeferi, noted biological anthropologist, whose experience conducting neuroanatomical comparisons of our primate predecessors, as well as typical and atypical human neuroanatomy, is helping to focus the search for causes of atypical behavioral conditions like autism and Williams Syndrome. Her work has pointed to neuroanatomical differences, on scales from whole brain structures, down to individual neurons and the genetics of neurodevelopment.

She reveals what she has found, and how this helps the Muotri Lab’s studies with brain organoids in the search for autism in our social brains.

Watch — Searching for Autism in our Social Brain.

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