
Being a parent often brings unexpected challenges, but for Dr. Madeline Oudin, the journey has been especially profound. As both a scientist and a mother, she is navigating uncharted territory to help her daughter Margot, who was born with SCN8A-related epilepsy. This rare genetic condition causes severe seizures and developmental challenges, profoundly affecting Margot’s daily life. In a moving talk, Dr. Oudin shares her remarkable story of resilience, determination, and the transformative power of science and community.
Margot’s diagnosis came with daunting obstacles. She faced frequent, uncontrollable seizures and developmental delays, leaving her family searching for answers. For Dr. Oudin and her husband, both scientists, the diagnosis was not just a personal blow but also a professional call to action. Combining their expertise in genetics and biology, they embarked on a mission to find solutions where none previously existed.
One of the most intricate areas of Dr. Oudin’s research is the development of Antisense Oligonucleotide (ASO) therapy. This experimental treatment seeks to address the genetic mutation underlying Margot’s epilepsy. While the potential benefits are significant, the challenges highlight the long road ahead. Alongside this research, Dr. Oudin explored alternative approaches, such as a ketogenic diet.
The journey hasn’t been easy. Balancing life as a mother and a scientist, Dr. Oudin shares the emotional highs and lows of tackling such a personal challenge. She also highlights the importance of community, emphasizing how sharing Margot’s story has connected her with other families and researchers, accelerating progress in the field. Through collaboration and perseverance, Dr. Oudin’s work is not only bringing hope to her own family but also paving the way for advancements that could benefit countless others.
Dr. Oudin’s story is one of hope, innovation, and the unyielding love of a mother determined to change her daughter’s future. Her talk is a must-watch for anyone interested in science, resilience, or the boundless potential of combining expertise with passion. Margot’s journey is a reminder of the power of perseverance and the breakthroughs that can happen when science and humanity come together.
To learn more, watch: Harnessing My Daughter’s Diagnosis to Drive Novel Treatments for Neurodevelopmental Disorders.