Category: Health and Medicine

Fighting Cancer with a Virus

8232Can cancer cells be killed without harming the healthy cells around them? A new clinical trial is testing that hypothesis using a treatment based on the vaccinia virus. Vaccinia has played a huge role in eradicating smallpox but is now taking on a new part in the fight against cancer.

Dr. Loren Mell, a radiation oncologist at UCSD Moores Cancer Center, explains how this treatment built on the vaccinia virus backbone may be the key to more effective cancer fighting tools. Dr. Mell and host Dr. David Granet discuss this current research and the importance of clinical trails for cancer patients. Dr. Mell is the Principal Investigator of many clinical trials at UCSD and oversees several nationally and industry-funded research grants.

Watch Fighting Cancer with a Virus.

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New Alzheimer’s Programs from the Brain Channel’s On Our Mind

Alzheimer's Disease - On Our MindWatch the latest Alzheimer’s Disease programs from the Brain Channel!

The Brain Channel’s flagship series On Our Mind is endeavoring in the next few months to take a closer look at Alzheimer’s disease. Join Dr. William Mobley as he meets with those on the front lines of this disease to discuss current and potential therapies, testing, clinical trials, neuropathology, public policy and so much more.

Online now:

1761Diagnosing Alzheimer’s Disease
How do you know when memory problems become more than just problems? Diagnosing Alzheimer’s disease can be challenging but new tests and scientific insight are making the process simpler and more accurate. Michael Rafii, MD, PhD joins William Mobley, MD, PhD to discuss when to see a doctor, what to expect during the diagnosis process, and other valuable information for patients and their families.


1761Developing New Drugs for Alzheimer’s Disease
What does the future hold for the treatment of Alzheimer’s disease? Steven L. Wagner, PhD joins William Mobley, MD, PhD to discuss the development of new drugs to aid in the fight. Wagner describes amyloid plaques as “the cholesterol of the brain” and is working to find a way to suppress its adverse effects.


1761Down Syndrome and Alzheimer’s Disease
By the age of 40, nearly all people with Down syndrome have the plaques and tangles associated with Alzheimer’s disease. Michael Rafii, MD, PhD joins William Mobley, MD, PhD to discuss why this occurs, the prevalence and progression of Alzheimer’s disease, potential treatment models and current research affecting this predisposed population.


1761Detecting Alzheimer’s Disease Earlier and Effectively
Early detection of Alzheimer’s disease – before symptoms are visible – may be a key to stopping the disease’s progression. What warning signs are researchers looking for and what tools can they use? Paul Aisen, MD joins William Mobley, MD, PhD to discuss optimal assessments for diagnosing the disease, novel tools making earlier diagnosis possible, and the road map to developing drugs to slow, halt, and prevent Alzheimer’s.


Watch all the programs in this informative series and stay tuned for upcoming episodes.

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New Research Techniques for Preeclampsia Using Stem Cells

8232What is the placenta?

The placenta is “transient organ,” meaning it’s only a part of us during our life in the womb. Because it provides oxygen and essential nutrients during development, it plays a pivotal role for fetal growth. As Dr. Mana Parast says quite simply, “None of us would be here without it.”

Preeclampsia is a disorder of the placenta that complicates 5-8% of all pregnancies worldwide and is the leading cause of maternal death in the developed world. It’s also the leading cause of fetal growth restriction and there’s no cure except to deliver the baby. That makes preeclampsia the number one cause of induced preterm delivery in the United States. Babies that survive often spend months in neonatal intensive care and have many complications and increase risk for heart disease and diabetes later in life.

In this video, CIRM grantee Dr. Parast, a UCSD perinatal pathologist, discusses her use of the induced pluripotent stem (iPS) cell technique to screen for drugs that might lead to a cure for preeclampsia. Also, Silvia Michelazzi, a preeclampsia survivor, and her husband Dr. Matteo Moretto-Zito share their daughter’s birth story.

Watch Modeling Preeclampsia with Stem Cells.

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Eating For Health (and Pleasure): The UCSF Guide to Good Nutrition

8232Healthy eating is not about strict dietary limitations, staying unrealistically thin, or depriving yourself of foods you love. Rather, it’s about feeling good, having more energy, and sustaining your mental disposition. If you feel overwhelmed by all the conflicting nutrition and diet advice out there, you are not alone.

UCSF Professor of Medicine Dr. Robert Baron and Registered Dietician and Diabetes Educator Katie Ferraro discuss eating healthy in this series from UCSF, Eating for Health (and Pleasure): The UCSF Guide to Good Nutrition.

8232How Do We Know What to Eat, Drink (and Take)?
Dr. Baron addresses this often perplexing question. He explains what you can do to improve your diet, as well as what supplements you should — and should NOT — be taking. You may be surprised at the evidence.

8232Dietary Guidelines: From Pyramid to Plate
65% of the world’s population live in countries where obesity kills more people than those who are underweight. Katie Ferraro, takes us through the history of the food pyramid and how to judge what to put on your plate to maintain healthy weight.

8232Dietary Fats: The Good, the Bad, the Ugly
Katie Ferraro explains a healthy person on 2,000 calorie diet per day should strive for 65 grams total fat, less than 20 grams saturated fat, zero grams trans fat and under 200 milligrams of dietary cholesterol. Learn more about each type of fat and how to identify which is in what food.

8232Understanding Obesity
Dr. Baron explains the prevalence of obesity and trends in obesity rates, then looks at what we can do about it. He takes a look at various popular diets along with surgical and medicine options and concludes that the goal is to be as fit as possible at your current weight and prevent further weight gain, then begin weight loss.

Browse all programs in the series, Eating for Health (and Pleasure): The UCSF Guide to Good Nutrition.

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New Techniques in Neurosurgery

27760An MRI in the OR? It just might be the wave of the future.

Imaging technology has made its way into the the operating room – giving neurosurgeons new insights and better options for patients. Brain tumors hiding beneath the opaqueness of the skull can now be seen in real time allowing the surgeon to not only design more direct pathways for treatment but also remove more of the tumor while protecting the delicate anatomy surrounding it.

A pioneer of this revolutionary technique, Dr. Clark Chen, joins our host Dr. David Grant to discuss how these new techniques not only benefit the surgeon but are creating better outcomes for the patient.

Watch Brain Tumors, Tractography, and Surgery in the MRI – Health Matters online now.

Explore more programs in the Health Matters series.

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