Category Archives: Science and Society

Combatting the Scourge

Malaria has been described as “the perennial scourge of mankind,” with over 200 million cases reported annually resulting in up to 750,000 deaths and incalculable misery. The disease is most common in the tropical and subtropical regions that surround the equator, including Sub-Saharan Africa, Latin America, and Asia, but it may be found in any region where climatic conditions favor the growth and spread of the mosquito-borne parasite.

On-going global eradication efforts employing pesticides have been successful in southern Europe and the southern United States, but less so elsewhere. In recent years genomics has taken center stage in malaria research with the sequencing of both the malarial parasite and the human genome. One experimental application of this research is the production of genetically-modified mosquitoes that do not transmit malaria. Another new and promising technique is the gene drive, which combats malaria by introducing disruptive genes into wild populations of mosquitoes that interfere with the development of females.

The use of such radical measures unavoidably prompts serious bioethical concerns, including the possibilities of unforeseen mutations and broader ecological impacts. Ethicists also question whether we have the right to potentially eliminate a species. In her self-described role as a “moral philosopher” Laurie Zoloth (University of Chicago) has written and lectured extensively about these issues, arguing that:

In the 1960s, the world agreed that smallpox was a species worth eliminating. We should feel the same way about A. gambiae. And isn’t deploying a gene drive that specifically targets the mosquito species that carries malaria far better than using chemical sprays, such as pyrethroids, organochlorines and DDT (still used in some countries) that indiscriminately target any insect?

Though malaria and other insect-borne diseases have historically been associated with Third World poverty, Zoloth notes these maladies are no longer the exclusive province of underdeveloped tropical countries. As climate change results in greater and more widespread extremes of temperature, rainfall, and humidity, the range of mosquitoes is likely to increase, and with them the diseases they transmit including malaria, dengue, yellow fever, and Zika. While acknowledging the dangers of meddling with the genetic status quo, Zoloth maintains that preoccupation with those risks is a luxury afforded only to those who are not at risk of losing a loved one to wrenching fevers and severe dehydration.

Zoloth concludes that in that light, gene drives and other genomic-based eradication methods represent the most moral and ethical choice available to scientists.

Watch May We Make the World?: Religious and Ethical Questions with Dr. Laurie Zoloth – Burke Lectureship

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Evolution and Creationism as Science and Myth

Myths symbolize ideas, values, history and other issues that are important to a people. They may be true or false, mundane or fantastic; their significance is their meaning, not their narrative content.

Science is a way of knowing about the natural world. Its conclusions tentatively may be true or false, but its significance is its explanatory power: one has confidence in the process of science, even though some explanations change over time.

Myth and science thus seem very different, but each has been utilized by proponents of both sides of the Christian creationism and evolution controversy. Understanding this role is essential in comprehending (much less mediating) this persistent conflict.

Eugenie C. Scott served as the executive director of the National Center for Science Education, an organization that works to keep publicly (though not scientifically) controversial topics like evolution and climate change in the public schools. Her work has involved a mixture of science, communication, religion, education, law, and community activism.

Watch Evolution and Creationism as Science and Myth

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Why Do People Reject Good Science?

Many people will consider factual information and it will change their understanding. But there are some for whom, “Providing more, accurate information doesn’t seem to change their opinions or make them alter their erroneous views,” says Eugenie Scott, Founding Executive Director of National Center for Science Education. For example, Americans have a much lower incidence of acceptance of evolution than people in any other developed country in the world. The same is true about the acceptance of anthropogenic climate change, despite the scientific evidence for both.

What explains this knowledge resistance?

We all view factual information through a filter of ideology, values, and group identification but these filters often make ideas very resistant to change because they prevent us from looking dispassionately at empirical evidence, facts and logic. Scott explores what drives knowledge resistance and what can break it down.

Eugenie C. Scott served as the executive director of the National Center for Science Education, an organization that works to keep publicly (though not scientifically) controversial topics like evolution and climate change in the public schools. Her work has involved a mixture of science, communication, religion, education, law, and community activism.

Watch Why Do People Reject Good Science?

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